April 9, 2019

Aisha Reynolds
General Counsel & Corporate Secretary
CrossFirst Bankshares, Inc.
11440 Tomahawk Creek Parkway
Leawood, Kansas 66211

       Re: CrossFirst Bankshares, Inc.
           Amendment No. 1 to
           Draft Registration Statement on Form S-1
           Submitted March 25, 2019
           CIK No. 0001458412

Dear Ms. Reynolds:

      We have reviewed your amended draft registration statement and have the
following
comments. In some of our comments, we may ask you to provide us with
information so we
may better understand your disclosure.

       Please respond to this letter by providing the requested information and
either submitting
an amended draft registration statement or publicly filing your registration
statement on
EDGAR. If you do not believe our comments apply to your facts and circumstances
or do not
believe an amendment is appropriate, please tell us why in your response.

      After reviewing the information you provide in response to these comments
and your
amended draft registration statement or filed registration statement, we may
have additional
comments.

Draft Registration Statement on Form S-1 Submitted March 25, 2109

Prospectus Summary
Competitive Strengths
Sophisticated Suite of Banking Services to Facilitate Full-Service Commercial
Relationships,
page 7

1.     Please revise the pie chart depicting Deposits as of December 31, 2018
here and on page
       94 under the title Business   Deposit Composition to reflect Time
Deposits greater than or
       equal to $100,000 to be 14.2% and Time Deposits less than $100,000 to be
17.3%
       consistent with the disclosure appearing on page 75 under the title MD&A
  Discussion
       and Analysis of Financial Condition   Deposits.
 Aisha Reynolds
FirstName Bankshares, Inc. Reynolds
CrossFirst LastNameAisha
Comapany NameCrossFirst Bankshares, Inc.
April 9, 2019
April 2 2019 Page 2
Page 9,
FirstName LastName
The Offering
Listing , page 12

2.       We note your disclosure here and on page 51 under the title Dilution
that all information
         in the prospectus excludes shares of common stock issuable upon the
exercise or
         settlement of equity awards, warrants, future awards under the 2018
Omnibus Equity
         Incentive Plan and common stock issuable under the Employee Stock
Purchase Plan at
         March 7, 2019. Please provide a reconciliation of the amount of common
stock issuable at
         12/31/18 as disclosed in the financial statements to March 7, 2019.
Management's Discussion and Analysis of Financial Condition and Results of
Operations
Discussion and Analysis of Financial Condition
Investment Portfolio, page 63

3.       We note the table which presents the fair value of investment
portfolio securities by their
         stated maturities, as well as the average yields for each maturity
range at December 31,
         2018 and December 31, 2017. While you disclose that certain
securities, primarily
         mortgage-backed securities, do not have a single maturity date and are
shown separately,
         these securities are presented by maturity ranges. Please revise the
table to be consistent
         with the disclosure presented in Note 2: Securities on page F-18.
Deposits, page 75

4.       We note the table of average deposit balances and weighted average
rates for the years
         ended December 31, 2018, 2017 and 2016. Please revise the average
balance amounts of
         NOW and savings and Money market deposits for the year ended December
31, 2018 to
         be consistent with the amounts presented in the average balance sheet
appearing on page
         56 under the title Management's Discussion And Analysis Of Financial
Condition And
         Results Of Operations   Discussion and Results of Operations   Year
Ended December
         31, 2018 vs. Year Ended December 31, 2017   Net Interest Income and
Net Interest
         Margin.
Capital Requirements , page 80

5.       We note the table of capital requirements applicable to the company
and the bank. Please
         revise the amounts of Regulatory capital ratio requirements for the
company for the year
         ended December 31, 2017 to be consistent with the related amounts
appearing in Note 12:
         Regulatory Matters on page F-36.
 Aisha Reynolds
CrossFirst Bankshares, Inc.
April 9, 2019
Page 3

       You may contact Christina Harley at 202-551-3695 or John Nolan at
202-551-3492 if
you have questions regarding comments on the financial statements and related
matters. Please
contact Jessica Livingston at 202-551-3448 or Pam Long at 202-551-3765 with any
other
questions.



FirstName LastNameAisha Reynolds                          Sincerely,
Comapany NameCrossFirst Bankshares, Inc.
                                                          Division of
Corporation Finance
April 9, 2019 Page 3                                      Office of Financial
Services
FirstName LastName